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What is UC-II® Collagen?

How will it help you renew your joint health? Read on to find out!

Experiencing Joint Discomfort?

Joints are specialised structures that connect two or more bones together to provide mobility and flexibility to your body. Every working joint endures daily wear and tear in addition to having pressure from supporting your body weight.

Joints consist of cartilage matrix surrounded by the lubricant (synovial fluid). All structures of the joint are reinforced by strong connective tissue (tendons) and muscles. Cartilage matrix is produced by the specialized cells called chondrocytes that arise from the specialized part of the bone. Cartilage slowly self-regenerates stimulated by joint movement and friction. Having healthy and renewable cartilage is imperative to maintaining a healthy active lifestyle and flexibility of your whole body well into the latter stages of life.

Joint discomfort and stiffness can severely limit your ability to be active and participate in social activities. It can be also very frustrating because it interferes with all major aspects of life involving movement. This impacts the quality of life and increases your dependence on others to do your own things, even as simple as tying your own shoes and looking after yourself.

You can start reducing your joint discomfort and become active again with UC-II® - a natural way of managing your joint health and preventing small issues from escalating further!

How Does UC-II Work?

UC-II is clinically proven to protect your joints! It contains a patented form of an undenatured collagen type II (UC-II) that has been clinically tested to protect your joints from excessive inflammation and consequent degradation, thus allowing enough time for the cartilage matrix to renew itself. Collagen type II is commonly found in all joints of your body and helps to maintain the integrity of the joint cartilage. Undenatured collagen type II in Caltrate UC-II is specifically processed and extracted using low temperature conditions to retain its native structure, thus making it effective.

Undenatured Collagen type II (UC-II) can support joints in ageing and be equally effective in preventing or reducing further damage caused by wear and tear due to daily activities and strenuous exercises by slowing down cartilage degradation and promoting collagen formation in the joint, and as consequence improving joint flexibility and mobility.

UC-II has been clinically proven to promote healthier joints by way of retraining your body's defence system to recognize undenatured collagen type II found in your joints as friendly material. Taking regular UC-II effectively prevents your immune cells from mounting continuous waves of attacks against your own joint tissue and at the same time stimulates chondrocytes to start producing more collagen, giving joints enough time to start rebuilding healthy cartilage. This process is called "oral tolerance" and is achieved by daily oral supplementation with UC-II to support your joint health.

Why is UC-II Better than Glucosamine & Chondroitin?

  • UC-II clinically proven to be more effective than glucosamine & chondroitin
    • 25% more effective in reducing pain1
    • 23% more effective in reducing joint stiffness1
  • 30% reduction in WOMAC physical function score vs Placebo
  • Protects joint cartilage
  • Smaller in size and only once a day dosing (compared to 2 larger tablets daily for glucosamine + chondroitin)

UC-II has been clinically proven to more effective than glucosamine + chondroitin! The results of a randomised, double-blind, placebo-controlled study1 have shown that UC-II is more effective than glucosamine hydrochloride + chondroitin sulphate in relieving joint discomfort and joint stiffness.

In this study, subjects with osteoarthritis were randomised to consume a daily dose of either 40mg of UC-II, 1500 mg glucosamine plus 1200 mg chondroitin, or a placebo for 180 days. The results of the study revealed that in patients taking regular UC-II, the overall WOMAC score (as a reference of pain and discomfort) was significantly reduced compared with the placebo group, with a significant reduction of parameters of joint stiffness and pain compared with glucosamine + chondroitin treatment group1.

UC-II works naturally with your body's defence mechanism to protect and recover joint cartilage by modifying the joint inflammation processes – the underlying mechanism behindjoint discomfort, rather than by working on the symptoms only2!

Take Caltrate® Joint Health UC-II® today and feel renewed joint mobility, and revitalised movement!

Find out more about the Caltrate® Joint Health UC-II® here, and how it can help you move as you desire!

1*Lugo JP et al., "Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study," Nutrition Journal, vol. 15, no. 1 (January 2016): 14